Targeting Survival Integration Site Selection by Retroviruses and LTR-Retrotransposons
نویسنده
چکیده
Replication of retroviruses and retrotransposons depends on selecting a favorable chromosomal site for integration of their genomic DNA. Different retroelements meet this challenge by targeting distinctive chromosomal regions. Despite these differences, recent data hints at a common targeting mechanism-tethering of integration complexes to proteins bound at favorable sites.
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ورودعنوان ژورنال:
- Cell
دوره 115 شماره
صفحات -
تاریخ انتشار 2003